C.STATION™
Optimize and streamline entire cell line development (CLD) workflows with the all-in-one automated workstation.
From single-cell cloning of transfected cells to selecting high-producing clones to upscaling, the C.STATION fully automates stable CLD for monoclonal antibody production.
- Preconfigured and validated protocols
- Flexibility and upscaling
- Proven technology
- Sterile workflow
- Shorter timelines and better outcomes
- Single point of contact
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Key Features & Benefits
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What is inside?
Single-cell cloning to meet regulatory requirements
The C.STATION integrates CYTENA’s flagship instrument, the UP.SIGHT™, to enable a probability of clonality >99.99% and fulfill required regulatory expectations. Double assurance of clonality is achieved through nozzle images and 3D Full Well Imaging, a new and innovative method that images the full volume of each well from the point of dispensing using the integrated imager. First, images are taken at the dispensing nozzle to ensure only one cell is placed in each well and nonclonal droplets are discarded. Then, the single cells are confirmed once more with 3D Full Well Imaging.
Tracking colony growth over time
Confluency, cell count and viability of clonal cells are effortlessly monitored by the UP.SIGHT. The C.STUDIO software lets you track growing colonies over the course of an experiment while the instrument enables you to rewind and replay images, providing a full picture of the CLD workflow. With the confluency tool, determine the right time point to pick clones for a larger volume plate format.
Comprehensive mAb titer monitoring for high-producing clone identification
The C.STATION comes with built-in titer quantification based on a plate-based assay using the F.QUANT. This makes it possible to screen hundreds of clones without user interaction. With the C.STUDIO, clone selection based on relative productivity is straight forward and guarantees data traceability.
Preconfigured and validated protocols
Optimized and validated protocols help generate stable cell lines and make laboratory automation best practices more accessible.
Flexibility and upscaling
The C.STATION gives you the flexibility to screen hundreds of clones for high titers. Easily upscale CLD by processing multiple runs at once for in-house or contract development manufacturing (CDM).
Proven technology
The C.STATION automates CLD workflows by integrating our proven technologies in single-cell dispensing, assurance of clonality, plate imaging, colony tracking and titer assessment all in a self-contained workstation.
Sterile workflow
HEPA filters within the C.STATION create a sterile environment throughout the entire workflow.
Shorter timelines and better outcomes
The C.STATION is ready to use straight from the box and full automation saves you time normally spent in the planning phase. Our proven technology within the workstation also reduces the risk of failures in the development process.
Single point of contact
CYTENA is your single point of contact for the entire workstation.
Impact Areas - Use Cases
Cell-Based Assays
Product Resources
Application Notes
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Years of History of Success and Growth
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