cell line development

Clonal cell line development is a crucial step in various applications including generating biopharmaceuticals (eg. monoclonal antibodies). Current workflows in cell line development have major drawbacks such as missing proof of clonality, inefficient single-cell isolation and reduced cell viability.

The single-cell printer technology offers documented proof of clonality and provides efficient and fast single-cell seeding combined with excellent cell viability and zero risk of crosscontamination.

The single-cell printer supports SLAS/SBS format 96-well and 384-well plates. A great variety of typical cell lines used in cell line development such as CHO-K1, HEK 293, L929 can be processed.

Discover the single-cell printer technology for your clonal cell line application.

proof of clonality

Proof of cell line clonality. Images taken during the selection and isolation process of single-cells.

before cell printing tracking a …

… cells' way towards nozzle

targeted single-cell

targeted single-cell with contour overlay

after cell printing, confirmation that cell left nozzle

Automated cell imager allow to verify single cells in each well and to monitor their growth (available from other manufacutures).